Protein homeostasis in mitochondria [electronic resource] : AAA+ chaperones & proteases / David A. Dougan.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Protein homeostasis: Publisher: London : Henry Stewart Talks, 2012Description: 1 online resource (1 streaming video file (22 min.) : color, sound)Subject(s): Homeostasis | Mitochondria | Molecular chaperones | Proteins -- Metabolism | Mitochondria -- metabolism | Mitochondrial Proteins -- metabolism | Molecular Chaperones -- metabolismOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Protein homeostasis in mitochondria -- Mitochondria play an important role in ageing and disease -- Quality control of mitochondria is controlled at three different levels -- Protein quality control (PQC) in mitochondria is maintained by mitochondrial chaperones and AAA+ proteases -- Following proteotoxic stress a specific mitochondrial unfolded protein response (mtUPR) is activated -- The AAA+ protease CLPXP is proposed to play a key role in mtUPR signaling -- A novel mtCLPX interacting protein that modulates the activity of mtCLPXP both in vitro and in vivo has been identified.
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Mode of access: World Wide Web.