Role of calnexin and calreticulin in protein homeostasis within the endoplasmic reticulum [electronic resource] / David B. Williams.

By: Williams, David B [spk]Material type: FilmFilmSeries: Henry Stewart talksBiomedical & life sciences collection. Protein homeostasis: Publisher: London : Henry Stewart Talks, 2012Description: 1 online resource (1 streaming video file (57 min.) : color, sound)Subject(s): Calcium-binding proteins | Endoplasmic reticulum | Protein folding | Calcium-Binding Proteins | Calnexin -- metabolism | Calreticulin -- metabolism | Endoplasmic Reticulum | Protein FoldingOnline resources: Click here to access online | Series
Contents:
Contents: Introduction to the endoplasmic reticulum -- Protein folding and quality control within the endoplasmic reticulum -- Asn-linked glycosylation and oligosaccharide processing -- Calnexin and calreticulin -- Structure and functions -- The Calnexin cycle -- Recognition of substrate polypeptide by calnexin and calreticulin -- The dual binding model -- Role of ERp57 in glycoprotein folding by calnexin and calreticulin -- Peptidyl prolyl isomerases within the endoplasmic reticulum -- ER-associated degradation -- Overview -- Recognition of misfolded glycoproteins -- The Glyco code of the ER.
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Animated audio-visual presentation with synchronized narration.

Title from title frames.

Contents: Introduction to the endoplasmic reticulum -- Protein folding and quality control within the endoplasmic reticulum -- Asn-linked glycosylation and oligosaccharide processing -- Calnexin and calreticulin -- Structure and functions -- The Calnexin cycle -- Recognition of substrate polypeptide by calnexin and calreticulin -- The dual binding model -- Role of ERp57 in glycoprotein folding by calnexin and calreticulin -- Peptidyl prolyl isomerases within the endoplasmic reticulum -- ER-associated degradation -- Overview -- Recognition of misfolded glycoproteins -- The Glyco code of the ER.

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