Innate immunity in the genitourinary tract [electronic resource] : genetics of susceptibility to disease or asymptomatic carriage / Catharina Svanborg.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Cells of the innate immune system: Publisher: London : Henry Stewart Talks, 2012Description: 1 online resource (1 streaming video file (49 min.) : color, sound)Subject(s): Host-bacteria relationships | Natural immunity | Urinary tract infections -- Immunology | Bacteriuria -- immunology | Genetic Predisposition to Disease -- genetics | Host-Pathogen Interactions | Immunity, Innate -- genetics | Signal Transduction -- immunology | Urinary Tract Infections -- immunologyOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
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Contents: Pathogens\Commensals at the mucosal level -- How pathogenic bacteria activate a host response -- Pathogen specific innate immune signaling -- Urinary tract infections (UTI) -- Uropathogenic E. coli vs. ABU strains -- TLR4, CXCR1, IRF3, IL8R role in UTI response -- Importance of identifying signaling pathways & crucial effector cells -- Acute/Chronic pyelonephritis & asymptomatic bacteriuria -- Genetics & UTI -- Researching disease-associated polymorphisms -- SNPs and their effect in APN & UTI -- Mutations in structural genes -- Response to infection in reporter assays -- Commensalism vs. Virulence.
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Mode of access: World Wide Web.