Vesicular release of glutamate mediates bidirectional signaling between astrocytes and neurons [electronic resource] / Vladimir Parpura.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Physiology and pathophysiology of neuroglia: Publisher: London : Henry Stewart Talks, 2012Description: 1 online resource (1 streaming video file (45 min.) : color, sound)Other title: Vesicular release of glutamate mediates bidirectional signalling between astrocytes and neuronsSubject(s): Cellular signal transduction | Neurophysiology | Astrocytes -- metabolism | Calcium -- metabolism | Glutamic Acid -- metabolism | Nervous System -- physiology | Signal TransductionOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Neuronal glutamate release -- Increases astrocytic intracellular Ca2+ -- Coordinates astrocytic network activity -- Activates astrocytic plasma membrane glutamate transporters -- Ca2+-dependent glutamate release from astrocytes -- Increases neuronal intracellular Ca2+ -- Evokes a slow inward current in neurons -- Increases neuronal excitability -- Modulates spontaneous and evoked synaptic transmission -- Promotes neuronal synchronization -- Causes long-term potentiation of synaptic transmission.
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Mode of access: World Wide Web.