Physiology and pathophysiology of microglia [electronic resource] / Uwe-Karsten Hanisch.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Physiology and pathophysiology of neuroglia: Publisher: London : Henry Stewart Talks, 2012Description: 1 online resource (1 streaming video file (41 min.) : color, sound)Subject(s): Central nervous system -- Pathophysiology | Microglia | Central Nervous System -- immunology | Central Nervous System -- physiopathology | Immunity, Innate | Microglia -- pathology | Microglia -- physiologyOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Physiology and pathophysiology of microglia -- Microglia -- resident innate immune cells of the CNS -- Approaches to the study of microglia -- Developmental origin and functions -- Developmental contributions and consequences of malfunction -- The concept of 'resting' microglia -- functions in the healthy adult CNS -- Tissue surveillance and synaptic nursing as house-keeping duties -- The concept of microglial 'activation' -- transformation to distinct activity states -- The concept of detrimental microglia -- Activation signals and response diversity -- Macrophages and microglia: diversity in response behaviour -- Elements of the microglial response repertoire -- Response dynamics -- Microglial phenotypes associated with phagocytosis -- Contributions of microglia in neurodegenerative diseases.
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Mode of access: World Wide Web.