ApoE4, the most prevalent genetic risk factor for Alzheimer's Disease [electronic resource] / Danny Michaelson.

By: Michaelson, Daniel [spk]Material type: FilmFilmSeries: Henry Stewart talksBiomedical & life sciences collection. Alzheimer's disease: Publisher: London : Henry Stewart Talks, 2012Description: 1 online resource (1 streaming video file (53 min.) : color, sound)Subject(s): Alzheimer's disease -- Genetic aspects | Alzheimer's disease -- Pathology | Alzheimer Disease -- genetics | Alzheimer Disease -- pathology | Apolipoprotein E4 | Risk FactorsOnline resources: Click here to access online | Series
Contents:
Contents: ApoE4 the most prevalent genetic risk factor of Alzheimer's disease -- The apoE4 molecule -- The associated brain pathology in man -- The mechanisms underlying the pathological effects of apoE4 -- The role of lipids in mediating the effects of apoE4 -- The role of Amyloid-beta in mediating the effects of apoE4 -- ApoE4 receptors -- ApoE4 catabolism -- ApoE4 targeted therapeutic approaches -- Therapeutic approaches based on the apoE4 molecule -- Therapeutic approaches based on preventing pathologic interactions with other systems.
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Animated audio-visual presentation with synchronized narration.

Title from title frames.

Contents: ApoE4 the most prevalent genetic risk factor of Alzheimer's disease -- The apoE4 molecule -- The associated brain pathology in man -- The mechanisms underlying the pathological effects of apoE4 -- The role of lipids in mediating the effects of apoE4 -- The role of Amyloid-beta in mediating the effects of apoE4 -- ApoE4 receptors -- ApoE4 catabolism -- ApoE4 targeted therapeutic approaches -- Therapeutic approaches based on the apoE4 molecule -- Therapeutic approaches based on preventing pathologic interactions with other systems.

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