Presynaptic plasticity [electronic resource] / Robert S. Zucker.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Synapses, neurotransmitters and receptor channels: Publisher: London : Henry Stewart Talks, 2014Description: 1 online resource (1 streaming video file (54 min.) : color, sound)Subject(s): Calcium -- Physiological effect | Neural transmission | Neuroplasticity | Synapses -- Physiology | Calcium -- physiology | Neuronal Plasticity -- physiology | Neurons -- physiology | Synapses -- physiology | Synaptic TransmissionOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: What is short-term synaptic plasticity? -- Use of quantal analysis to show that plasticity arises presynaptically -- Synaptic depression and the "Depletion Model" -- Relationship of depletion model parameters to binomial statistical parameters -- Refinements to the depletion hypothesis -- Origin of slow phases of depression -- Role of multiple vesicle pools -- Role of vesicle endocytosis -- Role for calcium in recovery -- Why depression is sometimes absent -- Other forms of depression -- Phases of synaptic enhancement: facilitation, augmentation, and potentiation -- Presynaptic electrical events in synaptic enhancement -- Calcium and the nonlinear summation single site hypothesis -- Kinetic components of calcium removal -- Multiple sites of calcium action -- Problems with identifying molecular mediators -- Candidate molecular mediators -- A comprehensive model of presynaptic plasticity -- Other forms of synaptic enhancement -- Computational roles of short-term synaptic plasticity -- Physiological roles of short-term synaptic plasticity.
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Mode of access: World Wide Web.