HSV vectors [electronic resource] : approaches to the treatment of chronic pain / Joseph C. Glorioso.

By: Glorioso, Joseph C [spk]Material type: FilmFilmSeries: Henry Stewart talksBiomedical & life sciences collection. Gene transfer and gene therapy: Publisher: London : Henry Stewart Talks, 2014Description: 1 online resource (1 streaming video file (38 min.) : color, sound)Other title: Herpes Simplex Virus vectorsSubject(s): Chronic pain -- Treatment | Gene therapy | Genetic vectors -- Therapeutic use | Viral genetics | Analgesics | Chronic Pain -- therapy | Gene Therapy -- methods | Gene Transfer Techniques | Genetic Vectors -- therapeutic use | Pain Management -- methods | Pharmacogenetics -- methods | Simplexvirus -- genetics | Viruses -- geneticsOnline resources: Click here to access online | Series
Contents:
Contents: HSV gene therapy for pain -- Criteria for vector engineering and gene delivery -- HSV gene expression and HSV vectors -- Treating pain with opioid peptides -- Spinal nerve ligation model of neuropathic pain -- Transduction of lumbar DRG with HSV vector -- Osteolytic sarcoma studies -- Clinical trial in terminal cancer patients -- Effect of glycine on nociceptive behavior -- Selective vector infection and expression -- Targeting transgene expression with promoters -- Gene expression constructs -- Promoter-regulated expression in embryonic DRG -- Comparing LAP, CMV & CGRP gene expression.
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Animated audio-visual presentation with synchronized narration.

Title from title frames.

Contents: HSV gene therapy for pain -- Criteria for vector engineering and gene delivery -- HSV gene expression and HSV vectors -- Treating pain with opioid peptides -- Spinal nerve ligation model of neuropathic pain -- Transduction of lumbar DRG with HSV vector -- Osteolytic sarcoma studies -- Clinical trial in terminal cancer patients -- Effect of glycine on nociceptive behavior -- Selective vector infection and expression -- Targeting transgene expression with promoters -- Gene expression constructs -- Promoter-regulated expression in embryonic DRG -- Comparing LAP, CMV & CGRP gene expression.

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