Lentiviral vectors [electronic resource] : design, biological properties, milestones and current major applications, hazards. Part 2 of 2 / Luigi Naldini.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Gene transfer and gene therapy: Publisher: London : Henry Stewart Talks, 2014Description: 1 online resource (1 streaming video file (38 min.) : color, sound)Other title: Lentiviral vectors : design, biological properties, milestones and current major applications, hazards. Part 2 of 2Subject(s): Gene therapy | Genetic transformation | Genetic vectors | Lentiviruses | Medical genetics | Viral genetics | Gene Transfer Techniques | Genetic Therapy -- methods | Genetic Vectors -- genetics | Hematopoietic Stem Cells | Lentivirus -- genetics | Virus Integration -- geneticsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Lentiviral vectors: applications, gene transfer efficiency and transgene expression -- Therapeutic potential of HSC gene therapy -- Vector integration site analysis -- Lentiviral-mediated HSC gene transfer -- Rationale for HSC gene therapy vs. BMT -- HSC gene transfer by LV: current issues -- Restriction factors for lentiviral gene transfer -- Ex vivo transduction by lentiviral vectors -- HSC gene transfer by LV: current goals -- Applications: ex vivo into hematopoietic stem cells, ex vivo into lymphocytes, In vivo gene transfer (liver and CNS) -- Systemic delivery of LV: current issues -- Direct LV injection into the CNS -- CNS gene transfer: current issues.
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Mode of access: World Wide Web.