Development of immunotherapies for type 1 diabetes [electronic resource] : value and limitations of mouse models / Matthias von Herrath.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Animal models in biomedical research: Publisher: London : Henry Stewart Talks, 2015Description: 1 online resource (1 streaming video file (40 min.) : color, sound)Subject(s): Animal models in research | Diabetes -- Animal models | Diabetes -- Immunotherapy | Drug development | Mice as laboratory animals | Biomarkers | Diabetes Mellitus, Experimental | Diabetes Mellitus, Type 1 -- immunology | Disease Models, Animal | Drug Discovery | Immunotherapy | Lymphocytic choriomeningitis virus | Mice, Inbred NOD | Models, Animal | Reproducibility of ResultsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: The use of animal models -- Strategy T1D: a prioritization process from mice to humans -- The non-obese diabetic (NOD) mouse model: reproducibility, increasing stringency level options, predictive potential of biomarkers -- Alternate models: The RIP-LCMV mouse -- Ongoing general challenges, mitigation actions & consequences.
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Mode of access: World Wide Web.