Arylamine N-acetyltransferases [electronic resource] : part 1 of 3 / Edith Sim.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Drug metabolizing enzymes : fundamentals, study methods, recent advances and clinical significance: Publisher: London : Henry Stewart Talks, 2016Description: 1 online resource (1 streaming video file (31 min.) : color, sound)Other title: Arylamine N-acetyltransferases 1Subject(s): Antibacterial agents | Biochemical markers | Breast -- Cancer | Drug development | Drugs -- Metabolism | Enzyme Inhibitors | Isoenzymes | Transferases | Antitubercular Agents | Arylamine N-Acetyltransferase -- antagonists & inhibitors | Arylamine N-Acetyltransferase -- genetics | Arylamine N-Acetyltransferase -- metabolism | Bacterial Infections -- drug therapy | Biomarkers | Breast Neoplasms -- diagnosis | Drug Discovery -- methods | Enzyme Inhibitors -- pharmacology | Ethnic Groups | Gene Expression Regulation, Enzymologic | Genetic Association Studies | Isoenzymes -- metabolism | Mice, Transgenic | Mycobacterium -- drug effects | Pharmaceutical Preparations -- metabolism | PharmacogeneticsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2007.
Contents: Mechanism of action -- Reaction substrates -- Isoform substrate profiles -- Isoenzymes NAT1 and NAT2 -- Regulation of gene expression -- Pharmacogenetics -- Phenotype/genotype correlation -- Ethnic variation -- Transgenic mouse models -- NAT protein structures -- NAT as a biomarker in breast cancer -- NAT inhibitors as diagnostic agents -- NAT in mycobacteria -- NAT inhibitors as an approach to potential anti-tubercular agents.
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Mode of access: World Wide Web.