The type I interferon system and viruses [electronic resource] / Adolfo Garcia-Sastre.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Viruses and viral diseases : emerging threats to humans and animals: Publisher: London : Henry Stewart Talks, 2018Description: 1 online resource (1 streaming video file (36 min.) : color, sound)Subject(s): Interferon | Virus diseases | Antiviral Agents | Interferon Type I -- metabolism | Interferon Type I -- physiology | Signal Transduction | Virus Diseases -- immunology | Viruses -- immunologyOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2007.
Contents: Introduction to the type I interferon (IFN) system -- Induction of type I IFN by viruses -- TLR sensors and cytoplasmic nucleic acid sensors -- Inhibition of nucleic acid sensing by RNA and DNA viruses -- Type I IFN signaling and its inhibition by viruses -- Activities of type I IFN inducible genes and their viral inhibitors -- General inhibition of host gene expression by viruses -- Coordination of immune responses by type I IFN -- Role of viral IFN antagonists in virus biology -- Applications of viruses with debilitated interferon antagonism.
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Mode of access: World Wide Web.