Expression vs. function of ABC transporters at the blood-brain barrier [electronic resource] / Jean-Michel Scherrmann.Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Blood-brain barrier : understanding the regulatory gatekeeper between brain and body: Publisher: London : Henry Stewart Talks, 2019Description: 1 online resource (1 streaming video file (42 min.) : color, sound)Other title: Expression versus function of ABC transporters at the blood-brain barrierSubject(s): Biological transport | Blood-brain barrier | Drug development | Proteins -- Metabolism | ATP Binding Cassette Transporter, Subfamily B, Member 1 | ATP Binding Cassette Transporter, Subfamily G, Member 2 | ATP-Binding Cassette Transporters | Blood-Brain Barrier -- metabolism | Gene Expression | Multidrug Resistance-Associated Proteins -- metabolismOnline resources: Click here to access online | Series
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2008.
Contents: Introduction to the ABC superfamily and the blood-brain barrier (BBB) -- ABCB and P-glycoprotein (ABCB1) at the BBB -- ABCG and BCRP (ABCG2) at the BBB -- ABCC and the Multi-Drug Resistance Proteins (MRPs) at the BBB -- ABC in isolated human brain microvessels -- Pre-clinical and clinical impact in central nervous system research and drug development.
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Mode of access: World Wide Web.