Microbial recognition and the immune response [electronic resource] / Dana Philpott.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Immune System - key concepts and questions: ; Henry Stewart talksBiomedical & life sciences collection. Molecular basis of bacterial infection: Publisher: London : Henry Stewart Talks, 2020Description: 1 online resource (1 streaming video file (29 min.) : color, sound)Subject(s): Bacterial diseases -- Immunological aspects | Immune system | Adaptive Immunity | Antibody Formation | Bacterial Infections -- immunology | Disease Resistance | Immunity, Innate | Inflammasomes | NF-kappa B | Nod1 Signaling Adaptor Protein | Nod2 Signaling Adaptor Protein | Shigella flexneri | Signal Transduction | Toll-Like Receptors | Virulence FactorsOnline resources: Click here to access online | Series (Immune System - key concepts and questions) | Series (Molecular basis of bacterial infection) Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2009.
Contents: How can our cells tell that something is foreign? -- Overview of innate immunity -- Cell signaling PRMs -- Toll-like receptors -- Shigella flexneri -- NLRs are related to plant R proteins involved in disease resistance -- NLRs: detectors of MAMPs and danger signals -- Proposed mechanism for Nod protein activation by a MAMP -- Alerting the cell: Nod1 activates NFkB -- Critical role of Nod1 in infected intestinal epithelial cells -- Proposed mechanism for NLRP protein activation by a DAMP -- The inflammasomes -- How do innate immune signals translate into adaptive immune responses? -- Implication of Nod1 and Nod2 in adaptive immune responses -- TLRs vs. Nods -- Nod1 is required for priming adaptive immunity -- What is the compartment that carries Nod1-specific function?
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Mode of access: World Wide Web.