Tolerance induction to clotting factors with monoclonal antibodies [electronic resource] / Luís Graça.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Monoclonal antibodies as therapeutic agents : fundamentals, therapeutic applications and latest advances: Publisher: London : Henry Stewart Talks, 2020Description: 1 online resource (1 streaming video file (30 min.) : color, sound)Subject(s): Hemophilia -- Immunological aspects | Hemophilia -- Treatment | Immunological tolerance | Monoclonal antibodies | Adjuvants, Immunologic -- pharmacology | Antibodies, Monoclonal -- administration & dosage | Antigen Presentation | Blood Coagulation Factors | FOXP3 protein, human | Hemophilia A -- drug therapy | Hemophilia A -- immunology | Immune Tolerance -- drug effects | Interleukin-10 | Lymphocyte Depletion | T-Lymphocytes, RegulatoryOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: The immunogenicity of foreign tissues and proteins -- Induction of immune tolerance with monoclonal antibodies -- Properties of therapeutic immune tolerance -- The challenges to achieve tolerance to clotting factors in hemophilia -- The importance of appropriate antigen presentation for effective immune tolerance induction -- Cellular and molecular mechanisms underlying immune tolerance: IL-10, Foxp3, regulatory T cells, and T cell depletion -- Different routes of antigen presentation can recruit different tolerance mechanisms.
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Mode of access: World Wide Web.