PI 3-kinases and lipid messengers [electronic resource] / Bart Vanhaesebroeck.Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease: Publisher: London : Henry Stewart Talks, 2020Description: 1 online resource (1 streaming video file (45 min.) : color, sound)Subject(s): Antineoplastic agents | Cellular signal transduction | Lipids | Phosphotransferases | Antineoplastic Agents -- pharmacology | Phosphatidylinositol 3-Kinases -- metabolism | Phosphoinositide-3 Kinase Inhibitors | Second Messenger Systems | Signal Transduction -- physiologyOnline resources: Click here to access online | Series
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2007.
Contents: Phosphoinositide lipids and their metabolism -- Lipid second messengers produced by PI 3-kinases (PI3Ks) -- PI3K lipids transduce signals via binding to lipid-binding modules in proteins -- Multiple PI3K isoforms with specific biological functions in mammals -- Aberrant PI3K activation in cancer, overgrowth and immunity -- Clinical trials with PI3K pathway inhibitors -- Approval and Challenges for PI3K inhibitors in cancer treatment.
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Mode of access: World Wide Web.