Laboratory methods for the in vitro study of drug metabolism [electronic resource] / Ritu Singh.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection: Publisher: London : Henry Stewart Talks, 2021Description: 1 online resource (1 streaming video file (37 min.) : color, sound)Subject(s): Drug development | Drugs -- Metabolism | Enzymes -- Metabolism | Drug Discovery -- methods | Enzyme Induction | Enzyme Inhibitors -- pharmacology | In Vitro Techniques | Inactivation, Metabolic | Kinetics | Metabolic Clearance Rate | Models, Biological | Pharmaceutical Preparations -- metabolismOnline resources: Click here to access online Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Major classes of drug-metabolizing enzymes -- Co-factor requirement for in vitro incubations -- Practical aspects of conducting in vitro assays -- In vitro assays conducted during drug discovery and development -- Clearance estimation -- Kinetic parameter determination -- Enzyme inhibition -- Enzyme induction -- Enzyme reaction phenotyping.
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Mode of access: World Wide Web.