Cytotoxic T lymphocytes [electronic resource] / Gillian M. Griffiths.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Immune system - key concepts and questions: Publisher: London : Henry Stewart Talks, 2021Description: 1 online resource (1 streaming video file (33 min.) : color, sound)Subject(s): Cancer -- Immunotherapy | Cell-mediated cytotoxicity | Killer cells | T cells | Actins | Cytotoxicity, Immunologic | Fas Ligand Protein | Immunotherapy | Lymphohistiocytosis, Hemophagocytic | Neoplasms -- therapy | Perforin | Receptors, Antigen, T-Cell | Receptors, Chimeric Antigen | T-Lymphocytes, CytotoxicOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Cytotoxic T Lymphocytes (CTLs) -- Mechanism of action of CTLs -- CTL and the microenvironment -- Cytolytic granules -- Perforin and Fas ligand -- The role of pioneer microtubules -- Familial Haemophagocytic Lymphohistiocytosis (FHL) -- Controlling CTL killing -- The role of actin and actin depletion -- CTLs are being harnessed in immunotherapies -- Co-stimulatory signals and TCRs -- CAR-T cells.
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Mode of access: World Wide Web.