Histone dynamics, heritability and variants [electronic resource] / Genevieve Almouzni.Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms: ; Henry Stewart talksBiomedical & life sciences collection. Epigenetics, chromatin, transcription and cancer: ; Henry Stewart talksBiomedical & life sciences collection. Eukaryotic gene regulation : from chromatin to transcription to mRNA processing: Publisher: London : Henry Stewart Talks, 2022Description: 1 online resource (1 streaming video file (38 min.) : color, sound)Subject(s): Chromatin | Epigenesis | Genetic regulation | Histones | Molecular chaperones | Chromatin Assembly and Disassembly | Chromatin -- genetics | DNA Replication | Epigenesis, Genetic -- genetics | Epigenesis, Genetic -- physiology | Eukaryotic Cells | Gene Expression Regulation | Histone Chaperones | Histone Code | Histones -- genetics | Histones -- physiology | Molecular Chaperones -- physiology | Transcription, GeneticOnline resources: Click here to access online | Series (Epigenetics : concepts, theories, paradigms and mechanisms) | Series (Eukaryotic gene regulation) | Series (Epigenetics, chromatin, transcription and cancer)
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2014.
Contents: DNA is organized into chromatin which promotes compaction and brings about additional information -- The histone code hypothesis -- Chromatin dynamics and heritability -- Factors involved in chromatin dynamics -- Nucleosomes disruption and assembly following DNA replication fork passage -- General steps in chromatin assembly -- Histone chaperones and their possible roles (CAF-1, HIRA, ...) -- Histone H3 variants and chromatin assembly coupled or not with DNA synthesis -- Specific histone deposition pathways for each variant? -- "de-novo deposition" in addition to recycling old histones -- The maintenance of patterns of modifications in specific domains: how to ensure heritability?
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Mode of access: World Wide Web.