Histone dynamics, heritability and variants [electronic resource] / Genevieve Almouzni.
Material type:
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2014.
Contents: DNA is organized into chromatin which promotes compaction and brings about additional information -- The histone code hypothesis -- Chromatin dynamics and heritability -- Factors involved in chromatin dynamics -- Nucleosomes disruption and assembly following DNA replication fork passage -- General steps in chromatin assembly -- Histone chaperones and their possible roles (CAF-1, HIRA, ...) -- Histone H3 variants and chromatin assembly coupled or not with DNA synthesis -- Specific histone deposition pathways for each variant? -- "de-novo deposition" in addition to recycling old histones -- The maintenance of patterns of modifications in specific domains: how to ensure heritability?
Access restricted to subscribers.
Mode of access: World Wide Web.