PI3K/AKT signaling In cancer (Record no. 77458)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02429ngm a2200385 a 4500 |
| 001 - CONTROL NUMBER | |
| control field | HST2881_1_3 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | UkLoHST |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m c |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr|cna|||a|||| |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | vz|czazum |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 120117s2011 enk|||||||||||s|||v|eng d |
| 028 50 - PUBLISHER NUMBER | |
| Publisher number | 2881 |
| Source | Henry Stewart Talks |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (UkLoHST)2160 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | UkLoHST |
| Language of cataloging | eng |
| Transcribing agency | UkLoHST |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Rosen, Neal, |
| Affiliation | (Memorial Sloan Kettering Cancer Center, USA) |
| Relator code | spk |
| 245 10 - TITLE STATEMENT | |
| Title | PI3K/AKT signaling In cancer |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | Neal Rosen. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | London : |
| Name of publisher, distributor, etc. | Henry Stewart Talks, |
| Date of publication, distribution, etc. | 2011. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (1 streaming video file (68 min.) : |
| Other physical details | color, sound). |
| 490 1# - SERIES STATEMENT | |
| Series statement | Protein phosphorylation, |
| International Standard Serial Number | 2056-452X |
| 500 ## - GENERAL NOTE | |
| General note | Animated audio-visual presentation with synchronized narration. |
| 500 ## - GENERAL NOTE | |
| General note | Title from title frames. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Contents: PI3K/AKT signal transduction pathway -- Tumors with frequent dysregulation of PI3K signalling -- Modalities for inhibiting PI3K-AKT signaling currently in development -- AKT1/2 inhibitor (Merck) -- PI3K/AKT in breast cancer -- AKTi-1/2 inhibits AKT signaling and causes G1 arrest -- The Herceptin-resistant -- Effect of AKT inhibition on glucose levels -- Mutated elements in mitogenic signaling pathways in tumors -- Coexistent K-Ras or B-Raf mutation -- Genes encoding several components of mitogenic signaling pathways are mutationally activated in tumors -- Integrators of multiple signaling pathways (OR-gates) -- The effects of combined inhibition of AKT and MAPK on the phosphorylation of translational regulatory proteins -- Knockdown of 4EBP1 expression -- Feedback inhibition of insulin/IGF-1 signaling -- The concept of feedback -- Clinical effects of Rapamycin-like drugs -- mTORC1 vs. AKT regulated feedback -- Clinical uses of AKT inhibitors. |
| 506 ## - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Access restricted to subscribers. |
| 538 ## - SYSTEM DETAILS NOTE | |
| System details note | Mode of access: World Wide Web. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cancer |
| General subdivision | Pathophysiology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cellular signal transduction. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Protein-tyrosine kinase |
| General subdivision | Inhibitors. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neoplasms |
| General subdivision | physiopathology. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Phosphatidylinositol 3-Kinase. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Proto-Oncogene Proteins c-akt. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Signal Transduction |
| General subdivision | physiology. |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Henry Stewart talks. |
| Name of part/section of a work | Biomedical & life sciences collection. |
| -- | Protein phosphorylation. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://hstalks.com/bs/2160/">https://hstalks.com/bs/2160/</a> |
| 856 42 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://hstalks.com/bs/p/531/">https://hstalks.com/bs/p/531/</a> |
| Materials specified | Series |
No items available.