Barrier mechanisms in the developing brain (Record no. 77113)

000 -LEADER
fixed length control field 02729ngm a2200457 a 4500
001 - CONTROL NUMBER
control field HST3437
003 - CONTROL NUMBER IDENTIFIER
control field UkLoHST
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS
fixed length control field m c
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr|cna|||a||||
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field vz|czazum
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 140422s2014 enk|||||||||||s|||v|eng d
028 50 - PUBLISHER NUMBER
Publisher number 3437
Source Henry Stewart Talks
035 ## - SYSTEM CONTROL NUMBER
System control number (UkLoHST)2721
040 ## - CATALOGING SOURCE
Original cataloging agency UkLoHST
Language of cataloging eng
Transcribing agency UkLoHST
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Saunders, Norman,
Dates associated with a name 1938-
Relator code spk
245 10 - TITLE STATEMENT
Title Barrier mechanisms in the developing brain
Medium [electronic resource] :
Remainder of title protection or vulnerability? /
Statement of responsibility, etc. Norman Saunders.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. London :
Name of publisher, distributor, etc. Henry Stewart Talks,
Date of publication, distribution, etc. 2014.
300 ## - PHYSICAL DESCRIPTION
Extent 1 online resource (1 streaming video file (57 min.) :
Other physical details color, sound).
490 1# - SERIES STATEMENT
Series statement The blood-brain barrier : understanding the regulatory gatekeeper between brain and body,
International Standard Serial Number 2056-452X
500 ## - GENERAL NOTE
General note Animated audio-visual presentation with synchronized narration.
500 ## - GENERAL NOTE
General note Title from title frames.
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Contents: The brain develops within a well-defined internal environment -- The properties of this internal environment are determined by transporters in the cellular interfaces between the blood, brain and cerebrospinal fluid -- The transporters are effective because the intercellular spaces between the cells in the interfaces are sealed by tight junctions -- The transporters are both influx and efflux and many are active very early in brain development -- Although brain barrier mechanisms are present very early in development they are vulnerable to pathological conditions e.g. inflammation, which may result in barrier dysfunction and damage to the fragile developing brain -- These mechanisms thus provide protection and a stable internal environment, but some may render the developing brain more vulnerable e. g. inward transport of toxins such as mercury via a normal amino acid transporter.
506 ## - RESTRICTIONS ON ACCESS NOTE
Terms governing access Access restricted to subscribers.
538 ## - SYSTEM DETAILS NOTE
System details note Mode of access: World Wide Web.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biological transport.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Blood-brain barrier.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Brain
General subdivision Growth.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Blood-Brain Barrier
General subdivision cytology.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Blood-Brain Barrier
General subdivision embryology.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Blood-Brain Barrier
General subdivision growth & development.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Blood-Brain Barrier
General subdivision metabolism.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Brain
General subdivision embryology.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Brain
General subdivision growth & development.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Capillary Permeability.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Carrier Proteins.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Intercellular Junctions
General subdivision metabolism.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Maternal Exposure.
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Henry Stewart talks.
Name of part/section of a work Biomedical & life sciences collection.
-- Blood-brain barrier : understanding the regulatory gatekeeper between brain and body.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://hstalks.com/bs/2721/">https://hstalks.com/bs/2721/</a>
856 42 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://hstalks.com/bs/p/277/">https://hstalks.com/bs/p/277/</a>
Materials specified Series

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