Dose-response Analysis With R (Record no. 73097)

000 -LEADER
fixed length control field 03631cam a2200505M 4500
001 - CONTROL NUMBER
control field 9781315270098
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220531132507.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS
fixed length control field m o d
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 190725s2018 xx o 000 0 eng d
040 ## - Cataloging Source
-- OCoLC-P
-- eng
-- OCoLC-P
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781315270098
-- (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 1315270099
-- (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781351981033
-- (electronic bk. : EPUB)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 135198103X
-- (electronic bk. : EPUB)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781351981040
-- (electronic bk. : PDF)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 1351981048
-- (electronic bk. : PDF)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781351981026
-- (electronic bk. : Mobipocket)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 1351981021
-- (electronic bk. : Mobipocket)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Canceled/invalid ISBN 9781138034310
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Canceled/invalid ISBN 1138034312
035 ## - SYSTEM CONTROL NUMBER
System control number (OCoLC)1109972695
Canceled/invalid control number (OCoLC)1111977079
035 ## - SYSTEM CONTROL NUMBER
System control number (OCoLC-P)1109972695
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RM301.8
072 #7 -
-- MAT
-- 029000
-- bisacsh
072 #7 -
-- MED
-- 096000
-- bisacsh
072 #7 -
-- PBT
-- bicssc
082 04 -
-- 615.1
-- 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Ritz, Christian,
Relator term author.
245 10 - TITLE STATEMENT
Title Dose-response Analysis With R
Medium [electronic resource].
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Name of publisher, distributor, etc. Chapman & Hall
Date of publication, distribution, etc. 2018.
300 ## - PHYSICAL DESCRIPTION
Extent 1 online resource
520 ## -
-- Nowadays the term dose-response is used in many different contexts and many different scientific disciplines including agriculture, biochemistry, chemistry, environmental sciences, genetics, pharmacology, plant sciences, toxicology, and zoology. In the 1940 and 1950s, dose-response analysis was intimately linked to evaluation of toxicity in terms of binary responses, such as immobility and mortality, with a limited number of doses of a toxic compound being compared to a control group (dose 0). Later, dose-response analysis has been extended to other types of data and to more complex experimental designs. Moreover, estimation of model parameters has undergone a dramatic change, from struggling with cumbersome manual operations and transformations with pen and paper to rapid calculations on any laptop. Advances in statistical software have fueled this development. Key Features: Provides a practical and comprehensive overview of dose-response analysis. Includes numerous real data examples to illustrate the methodology. R code is integrated into the text to give guidance on applying the methods. Written with minimal mathematics to be suitable for practitioners. Includes code and datasets on the book's GitHub: https://github.com/DoseResponse. This book focuses on estimation and interpretation of entirely parametric nonlinear dose-response models using the powerful statistical environment R. Specifically, this book introduces dose-response analysis of continuous, binomial, count, multinomial, and event-time dose-response data. The statistical models used are partly special cases, partly extensions of nonlinear regression models, generalized linear and nonlinear regression models, and nonlinear mixed-effects models (for hierarchical dose-response data). Both simple and complex dose-response experiments will be analyzed.
588 ## -
-- OCLC-licensed vendor bibliographic record.
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element MATHEMATICS / Probability & Statistics / General
Source of heading or term bisacsh
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element MEDICAL / Toxicology
Source of heading or term bisacsh
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Drugs
General subdivision Dose-response relationship.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Drugs
General subdivision Testing
-- Computer simulation.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Streibig, Jens C.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Jensen, Signe Marie.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Gerhard, Daniel.
856 40 -
-- Taylor & Francis
-- https://www.taylorfrancis.com/books/9781315270098
856 42 -
-- OCLC metadata license agreement
-- http://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf

No items available.

Technical University of Mombasa
Tom Mboya Street, Tudor 90420-80100 , Mombasa Kenya
Tel: (254)41-2492222/3 Fax: 2490571