Hoffmann, J. 1941-

The anti-microbial defense of Drosophila a paradigm for innate immunity / [electronic resource] : Jules A. Hoffmann. - London : Henry Stewart Talks, 2009. - 1 online resource (1 streaming video file (44 min.) : color, sound). - Innate immunity : host recognition and response in health and disease, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Innate immunity : host recognition and response in health and disease. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: The insect host defense is a multifaceted process -- Systemic anti-microbial response in Drosophila -- NF-kB: a central transactivator in immune responses -- Gene cascade -- The Toll pathway -- Imd pathway mutants are sensitive to bacterial infections -- Toll pathway mutants are sensitive to fungal infections -- TLR family members and their ligands -- The semmelweis (seml) mutation compromises the anti-gram-positive defense -- Structural aspects of PGRPs -- NF-kB activation by Toll and IMD in Drosophila -- Investigating the response of Drosophila to virus infection -- Response to RNA virus infections -- Keeping parasite numbers low: role of the mosquito immune system -- Losses and amplification of Plasmodium in A. gambiae -- Cactus -- ThioEster-containing Protein 1 (TEP1).

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Mode of access: World Wide Web.

2279 Henry Stewart Talks


Drosophila.
Immunity, Innate.
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