Kovanen, Petri.

Rupture of an atherosclerotic plaque a consequence of cholesterol accumulation and inflammation in the arterial intima / [electronic resource] : Plaque rupture Petri Kovanen. - London : Henry Stewart Talks, 2008. - 1 online resource (1 streaming video file (42 min.) : color, sound). - Genetics of cardiovascular disease : genetic interactions in a multifactorial disease, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Genetics of cardiovascular disease. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Inflammation and aetherosclerosis -- Immune activation -- Response to injury hypothesis -- Discovery of the pathophysiology of aetherosclerosis -- The cholesterol era -- The LDL level -- Arterial intima: the site of atherogenesis -- Genesis of thickening intima -- Adaptive intimal thickening -- Topology of coronary athero-sclerotic lesions -- Cholesterol in blood and in coronary arterial wall -- The "bad" LDL cholesterol and the "good" HDL cholesterol: an imbalance -- Coronary artery disease -- LDL-driven atherosclerosis leads to coronary stenosis -- Human coronary atheroma -- Atherothrombosis -- Plaque disruption -- Structure of an LDL particle -- Extracellular aggregated and fused LDL particles in the arterial intima of genetically hyperlipidemic mouse -- Extracellular lipid droplets in human atherosclerotic plaque -- Fatty streak formation in human fetal aortas is enchanced by maternal hypercholesterolemia.

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Mode of access: World Wide Web.

2159 Henry Stewart Talks


Atherosclerosis--physiopathology.
Cardiovascular Diseases--genetics.
Cholesterol.
Tunica Intima.
Technical University of Mombasa
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