Pan, D. J.

Control of tissue growth elucidation of the Hippo signaling pathway / [electronic resource] : Duojia (D.J.) Pan. - London : Henry Stewart Talks, 2008. - 1 online resource (1 streaming video file (34 min.) : color, sound). - The legacy of Drosophila genetics : from 'defining the gene' to 'analyzing genome function', 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Legacy of Drosophila genetics : from 'defining the gene' to 'analyzing genome function'. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Genetic screens for tumor suppressors in Drosophila -- Identification of the Warts tumor suppressor -- Identification of Hippo tumor suppressor and elucidation of the Hippo kinase cascade -- Discovery of Yorkie as the nuclear effector of the Hippo pathway -- Mechanism of Yorkie inactivation by phosphorylation -- Conservation of the Hippo kinase cascade in mammals -- The role of the Hippo pathway in mammalian organ size control and tumorigenesis.

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Mode of access: World Wide Web.

1792 Henry Stewart Talks


Drosophila--genetics.
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