Kent, Stephen B. H.

Solid-phase peptide synthesis [electronic resource] / Stephen Kent. - London : Henry Stewart Talks, 2008. - 1 online resource (1 streaming video file (57 min.) : color, sound). - Chemical biology : the role of chemistry in our fundamental understanding of biology, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Chemical biology : the role of chemistry in our fundamental understanding of biology. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Chemical structure of peptides -- Chemical peptide synthesis -- Classical solution synthesis -- Solid-phase peptide synthesis -- Chemistry of SPPS -- Automated solid-phase peptide synthesis -- Impact of SPPS -- Fundamentals of SPPS -- Synthesis takes place within the beads -- 'Super-elastic' swelling of peptide-resin beads -- Boc chemistry SPPS -- Fmoc chemistry SPPS -- 'Difficult' peptide sequences in SPPS -- Optimized solid-phase peptide synthesis -- Impact on SPPS of modern analytical methods -- Extensions of SPPS & applications of the solid-phase principle -- Scope and limitations of SPPS -- Impact of chemical ligation -- Total synthesis of human lysozyme.

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Mode of access: World Wide Web.

1751 Henry Stewart Talks


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