Nicchitta, Christopher V.

Endoplasmic reticulum, protein synthesis and translocation machinery [electronic resource] / Christopher V. Nicchitta. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (41 min.) : color, sound). - The endoplasmic reticulum : fundamentals and role in disease, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Endoplasmic reticulum : fundamentals and role in disease. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Protein sorting in the eukaryotic cell -- The discovery of the secretory pathway -- Overview discussion of the structure/function of the endoplasmic reticulum -- Experimental protocols and landmark experiments leading to the discovery of protein translocation -- The signal hypothesis -- Signal sequence structure -- Signal sequence recognition -- SRP receptor and targeting to the ER -- Mechanism of protein translocation and the protein translocation channel -- Translational regulation on the ER -- The unfolded protein response -- mRNA partitioning in the cell -- Are there alternative pathways for compartmentalizing protein synthesis?

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Mode of access: World Wide Web.

1537 Henry Stewart Talks


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