Neel, Benjamin G.
SH2-containing PTPs (Shps) in RTK signaling and disease [electronic resource] / Src homology 2-containing Protein Tyrosine Phosphatases (Shps) in Receptor Protein-Tyrosine Kinase signaling and disease Benjamin G. Neel. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (60 min.) : color, sound). - Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Introduction to the PTP superfamily -- Shps, history and overview -- Shp stucture: role of SH2 domains, PTP domains, C-tail -- catalytic mechanism -- Regulation by phosphotyrosyl peptides, phosphorylation, reactive oxygen species -- Overview of physiological functions -- Role in RTK signaling: regulation of Ras/Erk pathway; roles in other downstream cascades -- Shps in disease -- Key questions and challenges for the future.
Access restricted to subscribers.
Mode of access: World Wide Web.
1187 Henry Stewart Talks
Receptor Protein-Tyrosine Kinases.
Signal Transduction.
SH2-containing PTPs (Shps) in RTK signaling and disease [electronic resource] / Src homology 2-containing Protein Tyrosine Phosphatases (Shps) in Receptor Protein-Tyrosine Kinase signaling and disease Benjamin G. Neel. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (60 min.) : color, sound). - Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Introduction to the PTP superfamily -- Shps, history and overview -- Shp stucture: role of SH2 domains, PTP domains, C-tail -- catalytic mechanism -- Regulation by phosphotyrosyl peptides, phosphorylation, reactive oxygen species -- Overview of physiological functions -- Role in RTK signaling: regulation of Ras/Erk pathway; roles in other downstream cascades -- Shps in disease -- Key questions and challenges for the future.
Access restricted to subscribers.
Mode of access: World Wide Web.
1187 Henry Stewart Talks
Receptor Protein-Tyrosine Kinases.
Signal Transduction.