Hunter, Tony, 1943-
Receptor tyrosine kinases function, families and evolution / [electronic resource] : Tony Hunter. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (53 min.) : color, sound). - Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease, 2056-452X The world of hormones : molecular and physiological insights, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease. Henry Stewart talks. Biomedical & life sciences collection. World of hormones : molecular and physiological insights. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: History of protein phosphorylation -- Protein kinase bioinformatics -- History of tyrosine phosphorylation and functions of tyrosine kinases -- Genomic catalogues of protein kinases (kinomes) -- The human kinome -- The evolution of kinomes -- The human tyrosine kinase subfamily -- Receptor and nonreceptor tyrosine kinases -- Activation of receptor tyrosine kinases by ligand-induced dimerization -- Signal transduction pathways downstream of receptor tyrosine kinases -- Insulin and IOGF-1 receptor signaling via the mTOR pathway -- mTOR-S6 kinase feedback loop leading to downregulation of the IRS1 docking protein and insulin resistance -- History of Eph receptor tyrosine kinases and their ephrin ligands -- Bidirectional signaling via Eph-ephrin interactions on neighboring cells -- Simultaneous signaling by EphAs and ephrin As in motor neurons -- Compartmentalized signaling by receptor tyrosine kinases and their ligands through localization to discrete membrane domains -- Protein kinases and human disease -- Human cancer genes and protein kinases -- Protein kinases and phosphatases and cancer -- The long road to Gleevec.
Access restricted to subscribers.
Mode of access: World Wide Web.
1179 Henry Stewart Talks
Hormones.
Receptor Protein-Tyrosine Kinases.
Signal Transduction.
Receptor tyrosine kinases function, families and evolution / [electronic resource] : Tony Hunter. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (53 min.) : color, sound). - Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease, 2056-452X The world of hormones : molecular and physiological insights, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease. Henry Stewart talks. Biomedical & life sciences collection. World of hormones : molecular and physiological insights. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: History of protein phosphorylation -- Protein kinase bioinformatics -- History of tyrosine phosphorylation and functions of tyrosine kinases -- Genomic catalogues of protein kinases (kinomes) -- The human kinome -- The evolution of kinomes -- The human tyrosine kinase subfamily -- Receptor and nonreceptor tyrosine kinases -- Activation of receptor tyrosine kinases by ligand-induced dimerization -- Signal transduction pathways downstream of receptor tyrosine kinases -- Insulin and IOGF-1 receptor signaling via the mTOR pathway -- mTOR-S6 kinase feedback loop leading to downregulation of the IRS1 docking protein and insulin resistance -- History of Eph receptor tyrosine kinases and their ephrin ligands -- Bidirectional signaling via Eph-ephrin interactions on neighboring cells -- Simultaneous signaling by EphAs and ephrin As in motor neurons -- Compartmentalized signaling by receptor tyrosine kinases and their ligands through localization to discrete membrane domains -- Protein kinases and human disease -- Human cancer genes and protein kinases -- Protein kinases and phosphatases and cancer -- The long road to Gleevec.
Access restricted to subscribers.
Mode of access: World Wide Web.
1179 Henry Stewart Talks
Hormones.
Receptor Protein-Tyrosine Kinases.
Signal Transduction.