Serretti, Alessandro,

Genetic polymorphisms influencing the response of antidepressants [electronic resource] / Alessandro Serretti. - London : Henry Stewart Talks, 2012. - 1 online resource (1 streaming video file (52 min.) : color, sound). - Psychopharmacogenetics : genetic factors influencing the kinetics and dynamics of psychotropic drugs, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Psychopharmacogenetics : genetic factors influencing the kinetics and dynamics of psychotropic drugs. .

Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2007.

Contents: Pharmacogenetic studies in mood disorder -- Candidate genes as possible genetic predictors of antidepressant response efficacy -- Serotonin transporter gene (5-HTTLPR) -- Serotonin receptor 1A (5HT1A-C-1019G) -- G-protein beta3-subunit (Gbeta3-C825T) -- Serotonin receptor 2A (5HT2A -- 102TC) -- Tryptophan hydroxylase gene (TPH-A218C) -- Associations for FKBP5 and other unreplicated gene variants -- Follow up pharmacogenetic studies -- Circadian Locomotor Output Cycles Kaput (CLOCK-T3111C) gene variants are associated with insomnia and other features -- PER 15 variants and mood disorder phenotypes -- Neural networks: the example of 5-HTTLPR and TPH polymorphisms.

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Mode of access: World Wide Web.

1100 Henry Stewart Talks


Antidepressants--Mechanism of action.
Depression, Mental--Chemotherapy.
Pharmacogenetics.
Psychopharmacology.
Serotonin--Physiological effect.
Serotonin--Receptors.
Antidepressive Agents--pharmacology.
Depressive Disorder--drug therapy.
Depressive Disorder--genetics.
Neural Networks, Computer.
Polymorphism, Genetic.
Receptors, Serotonin.
Sleep Initiation and Maintenance Disorders.
Tryptophan Hydroxylase--genetics.
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