Sabatini, D. M.

The mTOR kinase as a target for anti-cancer drugs [electronic resource] / David M. Sabatini. - London : Henry Stewart Talks, 2010. - 1 online resource (1 streaming video file (38 min.) : color, sound). - Protein phosphorylation, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Protein phosphorylation. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Introduction to growth control -- Cell size changes in normal physiology -- Dual growth signals in multicellular organisms -- Rapamycin and its uses -- Discovery and function of mTOR growth pathways -- raptor and GbL -- The mTOR Complex 1 (mTORC1) pathway -- mTOR exists in two distinct protein complexes: mTORC1 and mTORC2 -- The role of the mTOR pathway in cancer.

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Mode of access: World Wide Web.

2718 Henry Stewart Talks


Neoplasms--drug therapy.
TOR Serine-Threonine Kinases.
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