Copeland, Robert Allen
Enzymology in drug discovery part 1 of 2 / [electronic resource] : Enzymology in drug discovery, part 1 of 2 Robert A. Copeland. - London : Henry Stewart Talks, 2013. - 1 online resource (1 streaming video file (42 min.) : color, sound). - Small molecule drug discovery, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Small molecule drug discovery. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Enzymes as targets for drug discovery -- Protein-ligand binding equilibria -- Enzyme reaction mechanisms -- Structure and function of enzyme active sites -- Measuring enzyme velocity in the laboratory -- Reversible modes of enzyme inhibition -- Enzyme inhibition as a mechanism of pharmacological intervention in disease -- Clinical value of different inhibition modalities -- Non-classical inhibition -- Enzyme assays and screening criteria -- Lead optimization -- Summary: basic information to look for.
Access restricted to subscribers.
Mode of access: World Wide Web.
3431 Henry Stewart Talks
Drugs--Design.
Enzyme inhibitors--Structure-activity relationships.
Enzyme inhibitors--Therapeutic use.
Enzymes.
Enzymology.
Pharmaceutical chemistry.
Drug Design.
Drug Discovery.
Enzyme Inhibitors--chemistry.
Enzyme Inhibitors--metabolism.
Enzyme Inhibitors--pharmacology.
Enzyme Inhibitors--therapeutic use.
Enzymes--metabolism.
Enzymology in drug discovery part 1 of 2 / [electronic resource] : Enzymology in drug discovery, part 1 of 2 Robert A. Copeland. - London : Henry Stewart Talks, 2013. - 1 online resource (1 streaming video file (42 min.) : color, sound). - Small molecule drug discovery, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Small molecule drug discovery. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Enzymes as targets for drug discovery -- Protein-ligand binding equilibria -- Enzyme reaction mechanisms -- Structure and function of enzyme active sites -- Measuring enzyme velocity in the laboratory -- Reversible modes of enzyme inhibition -- Enzyme inhibition as a mechanism of pharmacological intervention in disease -- Clinical value of different inhibition modalities -- Non-classical inhibition -- Enzyme assays and screening criteria -- Lead optimization -- Summary: basic information to look for.
Access restricted to subscribers.
Mode of access: World Wide Web.
3431 Henry Stewart Talks
Drugs--Design.
Enzyme inhibitors--Structure-activity relationships.
Enzyme inhibitors--Therapeutic use.
Enzymes.
Enzymology.
Pharmaceutical chemistry.
Drug Design.
Drug Discovery.
Enzyme Inhibitors--chemistry.
Enzyme Inhibitors--metabolism.
Enzyme Inhibitors--pharmacology.
Enzyme Inhibitors--therapeutic use.
Enzymes--metabolism.