Lipinski, Christopher A.,

Rules and filters and their impact on success in chemical biology and drug discovery [electronic resource] / Christopher A. Lipinski. - London : Henry Stewart Talks, 2014. - 1 online resource (1 streaming video file (78 min.) : color, sound). - Small molecule drug discovery, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Small molecule drug discovery. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Academic targets and the translational gap -- Chemistry & attrition (Reductionism, genomics and high throughput screening) -- Screening diverse compounds (advantages and disadvantages) -- Medicinal chemistry (A pattern recognition discipline) -- Biology and chemistry networks analysis -- Ligand efficiency and selectivity.

Access restricted to subscribers.


Mode of access: World Wide Web.

3678 Henry Stewart Talks


Drug development.
Drugs--Design.
Drugs--Research.
Pharmaceutical chemistry.
Chemistry, Pharmaceutical--methods.
Computational Biology--methods.
Drug Discovery--methods.
Drug Evaluation, Preclinical.
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