Schaffer, David V.

Directed evolution of novel adeno-associated viral vectors for gene therapy [electronic resource] / David Schaffer. - London : Henry Stewart Talks, 2014. - 1 online resource (1 streaming video file (52 min.) : color, sound). - Gene transfer and gene therapy, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Gene transfer and gene therapy. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Recent successes in gene therapy -- Problems in the field with naturally derived vectors -- Directed evolution as an approach to engineer optimal viral vector variants that meet clinical needs -- Examples: development of variants to evade neutralizing antibodies and evolution for enhanced delivery in the retina.

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Mode of access: World Wide Web.

3765 Henry Stewart Talks


Adenoviruses.
Gene therapy.
Genetic transformation.
Genetic vectors--Therapeutic use.
Retina--Diseases--Treatment.
Viral genetics.
Adenoviridae--genetics.
Dependovirus--genetics.
Gene Transfer Techniques.
Genetic Therapy--methods.
Genetic Therapy--trends.
Genetic Vectors--therapeutic use.
Retinal Diseases--therapy.
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