Goldberg, Alfred,
Protein degradation and defense against neurodegenerative disease part 1 of 2 / [electronic resource] : Protein degradation and defense against neurodegenerative disease, part 1 of 2 Alfred Goldberg. - London : Henry Stewart Talks, 2014. - 1 online resource (1 streaming video file (39 min.) : color, sound). - Protein homeostasis : folding proteins and maintaining the protein-protein interaction networks, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Protein homeostasis. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Neurodegenerative diseases with inclusion bodies associated with ubiquitin and proteasomes -- Abnormal proteins rapidly degraded in cells -- The ubiquitin-proteasome pathway -- Ubiquitin ligases important in neurological disease -- CHIP, Hsp70 and Hsp90 -- Conditions that induce muscle wasting -- Ubiquitin ligases in muscles atrophy -- P97/VCP -- Autophagy -- The Nedd4 ubiquitin-ligase and α-Synuclein -- The ESCRT pathway -- Proteasomal VS. lysosomal degradation (K48 and K63-linked chains) -- Expression of Nedd4 in Lewy bodies.
Access restricted to subscribers.
Mode of access: World Wide Web.
3675 Henry Stewart Talks
Brain--Aging--Molecular aspects.
Nervous system--Degeneration.
Protein folding.
Proteins--Metabolism.
Ubiquitin.
Heat-Shock Proteins.
Homeostasis.
Lewy Bodies.
Ligases.
Neurodegenerative Diseases--metabolism.
Proteasome Endopeptidase Complex.
Protein Folding.
Proteins--chemistry.
Proteins--metabolism.
Proteolysis.
Ubiquitin--metabolism.
Protein degradation and defense against neurodegenerative disease part 1 of 2 / [electronic resource] : Protein degradation and defense against neurodegenerative disease, part 1 of 2 Alfred Goldberg. - London : Henry Stewart Talks, 2014. - 1 online resource (1 streaming video file (39 min.) : color, sound). - Protein homeostasis : folding proteins and maintaining the protein-protein interaction networks, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Protein homeostasis. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Neurodegenerative diseases with inclusion bodies associated with ubiquitin and proteasomes -- Abnormal proteins rapidly degraded in cells -- The ubiquitin-proteasome pathway -- Ubiquitin ligases important in neurological disease -- CHIP, Hsp70 and Hsp90 -- Conditions that induce muscle wasting -- Ubiquitin ligases in muscles atrophy -- P97/VCP -- Autophagy -- The Nedd4 ubiquitin-ligase and α-Synuclein -- The ESCRT pathway -- Proteasomal VS. lysosomal degradation (K48 and K63-linked chains) -- Expression of Nedd4 in Lewy bodies.
Access restricted to subscribers.
Mode of access: World Wide Web.
3675 Henry Stewart Talks
Brain--Aging--Molecular aspects.
Nervous system--Degeneration.
Protein folding.
Proteins--Metabolism.
Ubiquitin.
Heat-Shock Proteins.
Homeostasis.
Lewy Bodies.
Ligases.
Neurodegenerative Diseases--metabolism.
Proteasome Endopeptidase Complex.
Protein Folding.
Proteins--chemistry.
Proteins--metabolism.
Proteolysis.
Ubiquitin--metabolism.