Frazier, Kendall S.,
Antisense oligonucleotides the promise and the problems / [electronic resource] : Kendall S. Frazier. - London : Henry Stewart Talks, 2015. - 1 online resource (1 streaming video file (45 min.) : color, sound). - The biomedical & life sciences collection, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Antisense oligonucleotide (ASOs) therapies -- Screening strategies for drug candidates -- Locked nucleic acid (LNA) gapmers -- Understanding off-target effects (OTEs) -- Mechanisms of ASO toxicity and clinical relevance -- New targets/delivery systems under development.
Access restricted to subscribers.
Mode of access: World Wide Web.
4027 Henry Stewart Talks
Antisense nucleic acids.
Drug development.
Toxicity testing.
Drug Discovery--methods.
Oligonucleotides, Antisense--adverse effects.
Oligonucleotides, Antisense--therapeutic use.
Oligonucleotides, Antisense--toxicity.
Patient Safety.
Toxicity Tests.
Antisense oligonucleotides the promise and the problems / [electronic resource] : Kendall S. Frazier. - London : Henry Stewart Talks, 2015. - 1 online resource (1 streaming video file (45 min.) : color, sound). - The biomedical & life sciences collection, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Antisense oligonucleotide (ASOs) therapies -- Screening strategies for drug candidates -- Locked nucleic acid (LNA) gapmers -- Understanding off-target effects (OTEs) -- Mechanisms of ASO toxicity and clinical relevance -- New targets/delivery systems under development.
Access restricted to subscribers.
Mode of access: World Wide Web.
4027 Henry Stewart Talks
Antisense nucleic acids.
Drug development.
Toxicity testing.
Drug Discovery--methods.
Oligonucleotides, Antisense--adverse effects.
Oligonucleotides, Antisense--therapeutic use.
Oligonucleotides, Antisense--toxicity.
Patient Safety.
Toxicity Tests.