Reardon, David A.

Immune checkpoint blockade in CNS tumors [electronic resource] / David A. Reardon. - London : Henry Stewart Talks, 2016. - 1 online resource (1 streaming video file (48 min.) : color, sound). - Immunotherapy of cancer, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Immunotherapy of cancer. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Immunotherapy in oncology -- CNS immunoprivilege -- Glioblastoma (GBM): complexity/redundancy/heterogeneity -- "Established" and "Advanced" GBM models -- Tumor-specific immune response in GBM -- Importance of heterogeneity -- Overcoming challenges for durable GBM benefit -- Neoantigen mutations -- Checkpoint blockade & immunologic memory -- GBM vaccines -- Personalized neoantigen vaccine ("NeoVax") -- Immunotherapy response assessment in neuro-oncology (iRANO) -- Clinical trials in neuro-oncology -- Immunosuppressive mechanisms in GBM -- Combination anti-tumor immunotherapy.

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Mode of access: World Wide Web.

4180 Henry Stewart Talks


Antineoplastic agents.
Brain--Cancer--Chemotherapy.
Brain--Cancer--Immunological aspects.
Brain--Cancer--Treatment.
Central nervous system--Cancer.
Glioblastoma Multiforme.
Immunotherapy.
Antineoplastic Agents--therapeutic use.
Brain Neoplasms--drug therapy.
Brain Neoplasms--immunology.
Central Nervous System Neoplasms--immunology.
Glioblastoma--immunology.
Glioblastoma--therapy.
Immunologic Factors--pharmacology.
Immunologic Memory.
Immunosuppressive Agents.
Immunotherapy.
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