Guengerich, F. Peter.

Cytochrome P450 1 family the roles of 1A1, 1A2 and 1B1 in drug metabolism / [electronic resource] : F. Peter Guengerich. - London : Henry Stewart Talks, 2016. - 1 online resource (1 streaming video file (45 min.) : color, sound). - Drug metabolizing enzymes : fundamentals, study methods, recent advances and clinical significance, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Drug metabolizing enzymes : fundamentals, study methods, recent advances and clinical significance. .

Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2007.

Contents: Family 1 P450 -- Substrates -- Regulation -- Polymorphisms -- Levels of activity and cancer -- Adverse drug reactions -- P450 systems and drug development -- Molecular epidemiology in cancer issues.

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Mode of access: World Wide Web.

1118 Henry Stewart Talks


Antineoplastic agents.
Cancer--Chemotherapy.
Cytochrome P-450--Physiological effect.
Drug development.
Drugs--Metabolism.
Antineoplastic Agents.
Cytochrome P-450 Enzyme System--genetics.
Cytochrome P-450 Enzyme System--metabolism.
Drug Discovery.
Drug-Related Side Effects and Adverse Reactions.
Inactivation, Metabolic.
Molecular Epidemiology.
Neoplasms--drug therapy.
Pharmaceutical Preparations--metabolism.
Polymorphism, Genetic.
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