Normolle, Daniel,

Case studies of adaptive early phase trials [electronic resource] / Daniel Normolle. - London : Henry Stewart Talks, 2016. - 1 online resource (1 streaming video file (44 min.) : color, sound). - Adaptive clinical trial design, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Adaptive clinical trial design. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: A model-based dose-escalation trial -- Bayesian modeling for personalized therapy -- Translation from animal to human dose-response models in a trial with a biomarker endpoint.

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Mode of access: World Wide Web.

4184 Henry Stewart Talks


Adaptive sampling (Statistics)
Animal models in research.
Antineoplastic agents--Testing.
Bayesian statistical decision theory.
Biochemical markers.
Clinical trials--Case studies.
Clinical trials--Statistical methods.
Drugs--Dose-response relationship.
Personalized medicine.
Research--Design.
Antineoplastic Agents--therapeutic use.
Bayes Theorem.
Biomarkers--metabolism.
Clinical Trials as Topic--methods.
Clinical Trials as Topic--statistics & numerical data.
Colon--metabolism.
Dose-Response Relationship, Drug.
Drug Dosage Calculations.
Fish Oils.
Liver Neoplasms--radiotherapy.
Maximum Tolerated Dose.
Models, Animal.
Pancreatic Neoplasms--drug therapy.
Pancreatic Neoplasms--radiotherapy.
Precision Medicine.
Research Design.
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