Mills, Gordon B.,

A systems approach to implementation of personalized cancer therapy [electronic resource] / Gordon B. Mills. - London : Henry Stewart Talks, 2017. - 1 online resource (1 streaming video file (51 min.) : color, sound). - Cancer therapies in the personalized medicine era, 2056-452X Systems biology, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Cancer therapies in the personalized medicine era. Henry Stewart talks. Biomedical & life sciences collection. Systems biology. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Targeted therapy for cancer -- Adaptive resistance: PI3K pathway -- Tumor heterogeneity -- Challenges & need for functional genomics -- Identification of PIK3R1 driver mutations -- Human proteomics atlas: reverse phase protein array (RPPA) -- Checkpoint inhibition as potential targets -- Synergy, operating model & strategy for combination therapies.

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Mode of access: World Wide Web.

4415 Henry Stewart Talks


Cancer--Genetic aspects.
Cancer--Treatment.
Cellular signal transduction.
Personalized medicine.
Systems biology.
Antineoplastic Agents.
Cell Cycle Checkpoints.
Combined Modality Therapy.
Immunotherapy.
Molecular Targeted Therapy.
Neoplasms--drug therapy.
Neoplasms--genetics.
Phosphatidylinositol 3-Kinases.
Precision Medicine--trends.
Protein Array Analysis.
Proteomics.
Signal Transduction--genetics.
Systems Biology--methods.
Systems Biology--trends.
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