Medina, Diego,
Lysosome much more than a degradative organelle / [electronic resource] : Diego Medina. - London : Henry Stewart Talks, 2018. - 1 online resource (1 streaming video file (17 min.) : color, sound). - Autophagy and lysosomal storage diseases, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Autophagy and lysosomal storage diseases. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Lysosome as degradative organelle -- Transcriptional regulation of lysosomal and autophagic function -- Promoting clearance through overexpression of TFEB in lysosomal storage disorders -- TFEB regulation by phosphorylation -- Imaging approaches to identify phosphatase regulating TFEB nuclear translocation -- Role of the lysosomal calcium channel TRPML1 in TFEB nuclear translocation.
Access restricted to subscribers.
Mode of access: World Wide Web.
4788 Henry Stewart Talks
Calcium--Physiological effect.
Cell death.
Cellular signal transduction.
Lysosomal storage diseases.
Lysosomes.
Autophagy--physiology.
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors--metabolism.
Calcium Channels.
Cytoplasm--metabolism.
Gene Expression Regulation.
Lysosomal Storage Diseases.
Lysosomes--metabolism.
Phosphorylation.
Protein Transport.
Transcription, Genetic.
Transient Receptor Potential Channels.
Lysosome much more than a degradative organelle / [electronic resource] : Diego Medina. - London : Henry Stewart Talks, 2018. - 1 online resource (1 streaming video file (17 min.) : color, sound). - Autophagy and lysosomal storage diseases, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Autophagy and lysosomal storage diseases. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Lysosome as degradative organelle -- Transcriptional regulation of lysosomal and autophagic function -- Promoting clearance through overexpression of TFEB in lysosomal storage disorders -- TFEB regulation by phosphorylation -- Imaging approaches to identify phosphatase regulating TFEB nuclear translocation -- Role of the lysosomal calcium channel TRPML1 in TFEB nuclear translocation.
Access restricted to subscribers.
Mode of access: World Wide Web.
4788 Henry Stewart Talks
Calcium--Physiological effect.
Cell death.
Cellular signal transduction.
Lysosomal storage diseases.
Lysosomes.
Autophagy--physiology.
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors--metabolism.
Calcium Channels.
Cytoplasm--metabolism.
Gene Expression Regulation.
Lysosomal Storage Diseases.
Lysosomes--metabolism.
Phosphorylation.
Protein Transport.
Transcription, Genetic.
Transient Receptor Potential Channels.