Chernoff, Yury,

Chaperones and prions [electronic resource] / Yury Chernoff. - London : Henry Stewart Talks, 2020. - 1 online resource (1 streaming video file (42 min.) : color, sound). - Prions and amyloids : self-propagating protein structures in mammals, yeast and fungi, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Prions and amyloids : self-propagating protein structures in mammals, yeast and fungi. .

Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2008.

Contents: Prion diseases -- Prions as self-propagating amyloids -- Yeast prions as protein-based heritable elements -- Prion detection -- Crucial role of the chaperone protein Hsp104 in the propagation of yeast prions -- Chaperone-mediated fragmentation turns amyloids into infectious or heritable prions -- Effects of the Hsp70 and Hsp40 proteins on yeast prions -- Other modulators of prion formation and propagation: cytoskeleton and ubiquitin system.

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Mode of access: World Wide Web.

1798 Henry Stewart Talks


Heat shock proteins.
Molecular chaperones.
Prion diseases.
Prions.
Yeast fungi.
Amyloid.
Cytoskeleton.
HSP40 Heat-Shock Proteins.
HSP70 Heat-Shock Proteins.
Prion Diseases.
Prions--metabolism.
Saccharomyces cerevisiae.
Ubiquitin.
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