Paul, Thomas A.,

Cancer-specific epigenetic alterations as investigated from a pharmaceutical perspective [electronic resource] / Thomas A. Paul. - London : Henry Stewart Talks, 2021. - 1 online resource (1 streaming video file (34 min.) : color, sound). - The biomedical & life sciences collection, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Chromatin dysregulation in cancer -- Features of epigenetic information in cells -- Mutated chromatin regulatory factors as tumor drivers -- Therapeutic rationale for the use of epigenetic drugs in oncology -- First generation epigenetic drugs: DNMT and HDAC inhibitors -- Novel therapeutic discoveries in oncology -- Biomarkers for patient selection.

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Mode of access: World Wide Web.

5208 Henry Stewart Talks


Antineoplastic agents--Development.
Cancer--Genetic aspects.
Epigenesis.
Antineoplastic Agents--pharmacology.
Chromatin Assembly and Disassembly--genetics.
Epigenesis, Genetic.
Histone Deacetylase Inhibitors.
Neoplasms--drug therapy.
Neoplasms--genetics.
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