Debyser, Zeger,
Cellular cofactors of HIV integrase from target identification to discovery of LEDGINs / [electronic resource] : Zeger Debyser. - London : Henry Stewart Talks, 2021. - 1 online resource (1 streaming video file (52 min.) : color, sound). - Antivirals : latest developments and future progress, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Antivirals. .
Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2011.
Contents: Cellular cofactors of HIV as novel antiviral targets -- LEDGF/p75 is a tethering factor of HIV integrase -- Identification of LEDGF/p75 as binding partner of integrase -- Characterization of the interaction -- Validation of integrase -- LEDGF/p75 interaction as antiviral target -- Assay and Drug Development -- Transportin -- SR2 is a nuclear import factor.
Access restricted to subscribers.
Mode of access: World Wide Web.
2829 Henry Stewart Talks
Antiviral agents.
Drug Development.
HIV (Viruses)--Enzymes--Inhibitors.
HIV infections--Treatment.
Antiviral Agents--pharmacology.
Drug Discovery.
HIV Infections--drug therapy.
HIV Integrase--metabolism.
HIV--drug effects.
Intercellular Signaling Peptides and Proteins.
lens epithelium-derived growth factor.
transportin SR2.
Cellular cofactors of HIV integrase from target identification to discovery of LEDGINs / [electronic resource] : Zeger Debyser. - London : Henry Stewart Talks, 2021. - 1 online resource (1 streaming video file (52 min.) : color, sound). - Antivirals : latest developments and future progress, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Antivirals. .
Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2011.
Contents: Cellular cofactors of HIV as novel antiviral targets -- LEDGF/p75 is a tethering factor of HIV integrase -- Identification of LEDGF/p75 as binding partner of integrase -- Characterization of the interaction -- Validation of integrase -- LEDGF/p75 interaction as antiviral target -- Assay and Drug Development -- Transportin -- SR2 is a nuclear import factor.
Access restricted to subscribers.
Mode of access: World Wide Web.
2829 Henry Stewart Talks
Antiviral agents.
Drug Development.
HIV (Viruses)--Enzymes--Inhibitors.
HIV infections--Treatment.
Antiviral Agents--pharmacology.
Drug Discovery.
HIV Infections--drug therapy.
HIV Integrase--metabolism.
HIV--drug effects.
Intercellular Signaling Peptides and Proteins.
lens epithelium-derived growth factor.
transportin SR2.